N200系列工业生产型高压微射流均质机

N200 Series High-Pressure Homogenizer

The  High-Pressure Homogenizer breaks through the limitations and bottlenecks of traditional stirring and dispersion technologies, effectively enhancing product value and maximizing economic benefits for users. In response to industry needs and user expectations, we have launched the  N200 model, designed for large-scale production. This equipment achieves a maximum operating pressure of 30,000 psi and a maximum flow rate of 4 L/min. Featuring modularly designed feeding, discharge, and temperature control units, users can select and assemble components based on actual requirements and consult with us to determine the optimal configuration. This ensures both the needs of small-scale trial production and the demands for stability, reliability, durability, and ease of cleaning in continuous production are met. We also offer optional validation documentation compliant with PIC/S cGMP standards, meeting the high regulatory requirements of the biopharmaceutical industry for manufacturing equipment.

The  N200 enhances energy efficiency and is suitable for continuous production. Its stable pressure output characteristics and maximum operating pressure of 30,000 psi have been proven to deliver more stable results in nano-dispersion, high-pressure homogenization, and cell disruption, with superior particle size distribution control. The equipment’s advantage of being free from grinding media contamination makes it ideal for developing high-value samples such as pharmaceuticals and novel materials. This model shares the same design principles as our R&D units, including a fixed geometry flow path and an impingement diamond reaction chamber. The concentrated collision energy distribution ensures uniformity and reproducibility in particle size distribution, and experimental data can be directly scaled up for production. We also offer factory-customized control and planning services for production-scale models to meet the production needs of different materials. Numerous customer references and market reputation confirm that the NanoLyzer N200 is the optimal solution for high-pressure homogenizer requirements in mass production.

Specifications

Pressure Range: Up to 30,000 psi (2,068 bar)

Flow Rate: Up to 4 L/min

Minimum Processing Volume: 10 L (with heat exchanger)

Max. Feed Temperature: 75 °C

Power Unit: Electro-hydraulic drive

Nozzle Material: Diamond, fixed geometry

Plunger Material: Ceramic

Enclosure: Stainless steel

Hold-up Volume: 8 L (with heat exchanger)

Dimensions (W × D × H): 250 × 120 × 170 cm

Weight: 1,600 kg

Utility Requirements

‧ Electrical: Three-phase 380 V, 60 Hz, 50 HP (37 kW)

‧ Cooling Water, hydraulic oil: 30 L/min @ 25 °C, PT 1/2"

‧ Cooling Water, product outlet: 60 L/min @ 16 °C, PT 1/2"

‧ Compressed Air: Minimum 0.65 m³/min @ 6.2 bar (23 SCFM @ 90 psi)

Dew point: -37 °C to -18 °C

Optional Configurations

Low-temperature water bath

Spare homogenization chamber

Temperature control for homogenization chamber

Product outlet temperature controller

Feeding and discharge container set

Automatic feeding system

Reverse cleaning function

Validation documents

Factory acceptance and final acceptance

Explosion-proof configuration

Plunger cooling system

Extended warranty service

N200 系列高压均质机

高压均质机能够突破传统搅拌分散技术的限制与瓶颈，有效提升产品附加值，为用户创造最大经济效益。基于对产业发展的支持与用户期望的回应，我们推出适用于规模化生产的N200机型。该设备最高操作压力可达30,000psi，最大流量达4升/分钟，采用模块化设计的进料区、出料区及温控单元，用户可根据实际需求选配组装各部件，并与我们商讨最优机型配置方案，兼顾小批量试产需求与连续生产对稳定性、可靠性、耐用性及易清洁性的要求。我们还可提供符合PIC/S cGMP标准的验证文件选配方案，满足生物医药行业对制药设备的高规格要求。

N200能有效提升能源利用效率，适合连续生产工况。其稳压式压力输出特性与最高30,000psi的操作压力配置，被证实可使纳米分散、高压均质及细胞破碎结果更加稳定，粒径分布控制效果更为优异。设备具备无研磨介质污染的优势，能满足药物及新型材料等高附加值样品的开发需求。本机型与公司研发机型均采用相同设计原理的固定几何流道及对撞式钻石反应腔，碰撞能量分布集中，可有效确保粒径分布的均一性与重现性，实验数据可直接进行工艺放大。我们还可为量产机型提供原厂定制化控制与规划服务，以满足不同物料的生产需求。众多客户的选用实例与市场口碑证实，N200是满足量产型高压均质机需求的最佳解决方案。

规格参数

压力范围：最高30,000 psi (2,068 bar)

流量：最高4升/分钟

最小处理量：10升（带热交换器）

最高进料温度：75 ℃

动力单元：电液驱动

喷嘴材质：金刚石，固定几何结构

柱塞材质：陶瓷

外壳：不锈钢

滞留体积：8升（带热交换器）

外形尺寸（宽×深×高）：250×120×170厘米

重量：1,600公斤

公用设施要求：

‧ 电源：三相380伏，60赫兹，50马力（37千瓦）

‧ 液压油冷却水：30升/分钟 @25℃，PT 1/2"接口

‧ 出料口冷却水：60升/分钟 @16℃，PT 1/2"接口

‧ 压缩空气：最低0.65立方米/分钟 @6.2 bar (23 SCFM @90psi)

露点温度-37℃至-18℃

可选配置

低温水槽

备用均质腔

均质腔温度控制

出料温度控制器

进出料容器组

自动进料系统

逆洗功能

验证文件

工厂验收与最终验收

防爆配置

柱塞冷却系统

延长保修服务