nG7400 Homogenising Systems

HOMOGENISING SYSTEMS

THE NEW HOME OF THE RANGE OF HIGH PRESSURE STANSTED HOMOGENISERS AND CELL DISRUPTER

"nm‑GEN‑7400" SERIES

ROBUST ‑ HIGH PERFORMANCE ‑ VERSATILE ‑ RELIABLE

NANOPARTICLES

LIPOSOMES

MICROEMULSIONS

DEAGGLOMERATION

CELL RUPTURE

HP PASTEURISATION

PRESSURES to 420 MPa 60,000 psi

FULLY CONTROLLABLE HOMOGENISING VALVES

MICRO CHANNEL DEVICE

BACK PRESSURE CONTROL

PROCESS TEMPERATURE CONTROL

EASY TO USE, CLEAN & MAINTAIN

REPRODUCIBLE RESULTS

SCALE UP

The nm‑GEN 7400 Series "Hy‑Drive" series of homogenisation / cell rupture systems have been developed to meet the special requirements associated with biotechnology, chemical and pharmaceutical processing applications. 

These systems complimented by smaller and larger models ranges offering processing from a  few ml to many m3.

The nm‑GEN‑7400 Series is suitable for pilot and production applications. 

The processing module is fully enclosed and the systems incorporate synchronised pair(s) of electro‑hydraulic high pressure intensifiers. These intensifiers feed the product at high pressure through a pressure processing head.

STANSTED high pressure homogenisers offer optimal processing by providing the user with the both Piston Gap homogenising valves or a Micro Channel Device (interaction chamber). Systems may be supplied with either or both options depending on the optimal choice the processing application. 

Our piston gap devices offer market leading pressure capability to 420 MPa (60,000 psi , 4200bar) and the range includes a number of optimised geometric patterns and profiles for optimal performance in each application. These devices incorporate advanced hard materials for optimal wear resistance and are simple to clean and maintain.

Our micro channel devices provide multiple configurations including “Z” and “Y” paths a range of channels sized for control of shear rates Our assemblies incorporate hard wearing polycrystalline diamond channels and assemblies by be simply opened and reassembled for cleaning, inspection and refurbishment.

System control is provided through a dedicated PLC with HMI or IPC with touch screen interface. Systems are designed to provide compliance with cGMP & FDA‑GMP. Systems can be offered with IQ/OQ documentation, full materials certification. 21 CFR part 11 compliance can be provided . Production pharmaceutical applications are offered with finely polished finish on wetted surfaces, CIP and SIP capabilities Systems can be supplied with many options to allow custom configuration, so of these include 

Back Pressure Module. A second stage homogenisation valve for us in the range 2‑20% of system maximum working pressure

Micro channel processing modules (for use up to 420 MPa (60,000 psi , 4200 bar)

Outlet Heat Exchanger. May be used to cool or heat product as required. Suitable for connection to external fluid circulation systems ‑20°C to +120°C

Inlet Heat Exchanger. May be used to cool or heat product as required. Suitable for connection to external fluid circulation systems ‑20°C to +120°C

Pressurised feed reservoir for use with high viscosity products.

The nm‑GEN‑7400 series is designed to provide the ultimate tool for R & D STANSTED and Production applications. The range has market leading pressure capability and construction incorporates the most advanced corrosion resistant materials and latest manufacturing techniques to ensure exceptional performance and reliability. 

Attention to detail in design and manufacture ensures wetted surfaces our suitably polished, high pressure ram plungers and primary wear surfaces utilise super hard materials and ceramics. We retain full documentation for materials and instrumentation to ensure all appropriate documentation is available for system validation. 

Our latest generate control interface combines a touch screen HMI / IPC and PLC combination with advanced control logic and safety interlocking for the system. Our menu driven user interface allows operator to easily set up and control processing primary processing parameters and to data log, record, store and retransmit process data for full integration into production lines.

SERVICES

Electrical Supply

3.7‑4 kW systems

208‑460V 3ph 50/60Hz

Compressed Air (or nitrogen)

6 barg (75 psig) minimum

10 barg (150 psig) maximum

Cooling Fluid Drive System

Inlet connection G 1/2 

Outlet connection G 1/2

0.2 barg (3 psig) minimum

3.0 barg (45 psig) maximum

+4°C minimum

+30°C maximum

Cooling / Heating Fluid

Outlet Heat Exchanger

(if required)

Inlet connection G 1/2 

Outlet connection G 1/2 

0.2 barg (3 psig) minimum

3.0 barg (45 psig) maximum

‑20°C minimum

+80°C maximum

PHYSICAL DATA

Width 1000 mm

Depth 800 mm

Height 2000 mm

Weight 475 kg ‑ 550

Depending on model

Process Connections

Inlet connection 3/4" Triclamp

Outlet connection 1/2" Triclamp

STANSTED bench top systems complement the range of large scale systems. On left small scale production pharmaceutical production system with CIP and SIP capacility and HMI/PLC control with touch operation

STANSTED pressure intensifiers. Graphic above (left) shows a typical STANSTED  twin intensifier configuration. The graphic on the right shows the pressure vs time profile for a normal intensifier system and the bottom right the pressure vs time profile for a synchronised intensifier pair. Smooth pressure delivery reduces fatigue and ensures a more unitform STANSTED processing