N200 Series High-Pressure Microfluidizer Homogenizer

N200 Series High-Pressure Homogenizer

The  High-Pressure Homogenizer breaks through the limitations and bottlenecks of traditional stirring and dispersion technologies, effectively enhancing product value and maximizing economic benefits for users. In response to industry needs and user expectations, we have launched the  N200 model, designed for large-scale production. This equipment achieves a maximum operating pressure of 30,000 psi and a maximum flow rate of 4 L/min. Featuring modularly designed feeding, discharge, and temperature control units, users can select and assemble components based on actual requirements and consult with us to determine the optimal configuration. This ensures both the needs of small-scale trial production and the demands for stability, reliability, durability, and ease of cleaning in continuous production are met. We also offer optional validation documentation compliant with PIC/S cGMP standards, meeting the high regulatory requirements of the biopharmaceutical industry for manufacturing equipment.

The  N200 enhances energy efficiency and is suitable for continuous production. Its stable pressure output characteristics and maximum operating pressure of 30,000 psi have been proven to deliver more stable results in nano-dispersion, high-pressure homogenization, and cell disruption, with superior particle size distribution control. The equipment’s advantage of being free from grinding media contamination makes it ideal for developing high-value samples such as pharmaceuticals and novel materials. This model shares the same design principles as our R&D units, including a fixed geometry flow path and an impingement diamond reaction chamber. The concentrated collision energy distribution ensures uniformity and reproducibility in particle size distribution, and experimental data can be directly scaled up for production. We also offer factory-customized control and planning services for production-scale models to meet the production needs of different materials. Numerous customer references and market reputation confirm that the NanoLyzer N200 is the optimal solution for high-pressure homogenizer requirements in mass production.

Specifications

Pressure Range: Up to 30,000 psi (2,068 bar)

Flow Rate: Up to 4 L/min

Minimum Processing Volume: 10 L (with heat exchanger)

Max. Feed Temperature: 75 °C

Power Unit: Electro-hydraulic drive

Nozzle Material: Diamond, fixed geometry

Plunger Material: Ceramic

Enclosure: Stainless steel

Hold-up Volume: 8 L (with heat exchanger)

Dimensions (W × D × H): 250 × 120 × 170 cm

Weight: 1,600 kg

Utility Requirements

‧ Electrical: Three-phase 380 V, 60 Hz, 50 HP (37 kW)

‧ Cooling Water, hydraulic oil: 30 L/min @ 25 °C, PT 1/2"

‧ Cooling Water, product outlet: 60 L/min @ 16 °C, PT 1/2"

‧ Compressed Air: Minimum 0.65 m³/min @ 6.2 bar (23 SCFM @ 90 psi)

Dew point: -37 °C to -18 °C

Optional Configurations

Low-temperature water bath

Spare homogenization chamber

Temperature control for homogenization chamber

Product outlet temperature controller

Feeding and discharge container set

Automatic feeding system

Reverse cleaning function

Validation documents

Factory acceptance and final acceptance

Explosion-proof configuration

Plunger cooling system

Extended warranty service